Webster LR, Smith MD, Unal C, Finn A (Source: Journal of Pain Research)
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Category Archives: Methadone Information Feed
Low dose naloxone provides an abuse deterrent effect to buprenorphine
Webster LR, Smith MD, Unal C, Finn A (Source: Journal of Pain Research)
The Cocaine Use Reduction with Buprenorphine study: Cocaine use findings
Aims: The Cocaine Use Reduction with Buprenorphine (CURB) study, conducted under the National Drug Abuse Treatment Clinical Trials Network, investigated the safety and effectiveness of buprenorphine/naloxone (BUP, as Suboxone®) provided on a platform of extended-release injectable naltrexone (XR-NTX, as Vivitrol®) for reducing cocaine use in participants who met DSM- IV criteria for cocaine dependence and past or current opioid dependence or abuse. (Source: Drug and Alcohol Dependence)
Pilot study of atomoxetine for BUP/NX-maintained patients with co-occurring opioid and ATS use disorder
Aims: To evaluate the tolerability, acceptability, and potential efficacy of the selective norepinephrine transporter inhibitor atomoxetine for treating amphetamine-type stimulant (ATS) use disorder in patients receiving buprenorphine/naloxone (BUP/NX). (Source: Drug and Alcohol Dependence)
Intranasal buprenorphine alone and in combination with naloxone: Reinforcing efficacy and abuse liability in physically dependent opioid abusers
Aims: Buprenorphine/naloxone (BUP/NX) was designed to prevent misuse by the intravenous (IV) route, as high naloxone IV bioavailability may precipitate withdrawal. We previously demonstrated that intranasal (IN) administration of BUP/NX results in appreciable absorption of naloxone. The present study explored whether IN BUP/NX has lower abuse potential and reinforcing efficacy compared to IN BUP alone in opioid dependent individuals. (Source: Drug and Alcohol Dependence)
Alcohol and tobacco use in cocaine-dependent participants provided treatment with buprenorphine/naloxone and naltrexone
Aims: Many individuals with cocaine use disorders also use alcohol and tobacco. A recent study conducted by NIDA’s Clinical Trials Network investigated pharmacotherapy for treatment of cocaine use disorders and also assessed alcohol and tobacco use. (Source: Drug and Alcohol Dependence)
MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Pilot study of atomoxetine for BUP/NX-maintained patients with co-occurring opioid and ATS use disorder
Aims: To evaluate the tolerability, acceptability, and potential efficacy of the selective norepinephrine transporter inhibitor atomoxetine for treating amphetamine-type stimulant (ATS) use disorder in patients receiving buprenorphine/naloxone (BUP/NX). (Source: Drug and Alcohol Dependence)
The Cocaine Use Reduction with Buprenorphine study: Cocaine use findings
Aims: The Cocaine Use Reduction with Buprenorphine (CURB) study, conducted under the National Drug Abuse Treatment Clinical Trials Network, investigated the safety and effectiveness of buprenorphine/naloxone (BUP, as Suboxone®) provided on a platform of extended-release injectable naltrexone (XR-NTX, as Vivitrol®) for reducing cocaine use in participants who met DSM- IV criteria for cocaine dependence and past or current opioid dependence or abuse. (Source: Drug and Alcohol Dependence)
Intranasal buprenorphine alone and in combination with naloxone: Reinforcing efficacy and abuse liability in physically dependent opioid abusers
Aims: Buprenorphine/naloxone (BUP/NX) was designed to prevent misuse by the intravenous (IV) route, as high naloxone IV bioavailability may precipitate withdrawal. We previously demonstrated that intranasal (IN) administration of BUP/NX results in appreciable absorption of naloxone. The present study explored whether IN BUP/NX has lower abuse potential and reinforcing efficacy compared to IN BUP alone in opioid dependent individuals. (Source: Drug and Alcohol Dependence)
MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
Alcohol and tobacco use in cocaine-dependent participants provided treatment with buprenorphine/naloxone and naltrexone
Aims: Many individuals with cocaine use disorders also use alcohol and tobacco. A recent study conducted by NIDA’s Clinical Trials Network investigated pharmacotherapy for treatment of cocaine use disorders and also assessed alcohol and tobacco use. (Source: Drug and Alcohol Dependence)