In conclusion, differences in respiratory effects between BUP/NLX and BUP are only significant in combination with DZP, with increased depression in naive rats but reduced depression in in BUP-tolerant rats. However, BUP/NLX benefits in humans remain to be determined.
PMID: 24769261 [PubMed – as supplied by publisher] (Source: Toxicology Letters)
Category Archives: Methadone Information Feed
Respiratory effects of buprenorphine/naloxone alone and in combination with diazepam in naive and tolerant rats.
In conclusion, differences in respiratory effects between BUP/NLX and BUP are only significant in combination with DZP, with increased depression in naive rats but reduced depression in in BUP-tolerant rats. However, BUP/NLX benefits in humans remain to be determined.
PMID: 24769261 [PubMed – as supplied by publisher] (Source: Toxicology Letters)
Abuse and diversion of buprenorphine sublingual tablets and film – Lavonas EJ, Severtson SG, Martinez EM, Bucher-Bartelson B, Le Lait MC, Green JL, Murrelle LE, Cicero TJ, Kurtz SP, Rosenblum A, Surratt HL, Dart RC.
Buprenorphine abuse is common worldwide. Rates of abuse and diversion of three sublingual buprenorphine formulations (single ingredient tablets; naloxone combination tablets and film) were compared. Data were obtained from the Researched Abuse, Diversion, … (Source: SafetyLit: All (Unduplicated))
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Abuse and diversion of buprenorphine sublingual tablets and film – Lavonas EJ, Severtson SG, Martinez EM, Bucher-Bartelson B, Le Lait MC, Green JL, Murrelle LE, Cicero TJ, Kurtz SP, Rosenblum A, Surratt HL, Dart RC.
Buprenorphine abuse is common worldwide. Rates of abuse and diversion of three sublingual buprenorphine formulations (single ingredient tablets; naloxone combination tablets and film) were compared. Data were obtained from the Researched Abuse, Diversion, … (Source: SafetyLit: All (Unduplicated))
Millennium Treatment Group Now Prescribing Suboxone for Detox
Suboxone has become a popular medication to use in detox from alcohol and other opiate addictions.(PRWeb March 14, 2014)Read the full story at http://www.prweb.com/releases/2014/03/prweb11671625.htm (Source: PRWeb: Medical Pharmaceuticals)
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Millennium Treatment Group Now Prescribing Suboxone for Detox
Suboxone has become a popular medication to use in detox from alcohol and other opiate addictions.(PRWeb March 14, 2014)Read the full story at http://www.prweb.com/releases/2014/03/prweb11671625.htm (Source: PRWeb: Medical Pharmaceuticals)
Barriers to primary care physicians prescribing of buprenorphine for opioid addiction
Buprenorphine-naloxone is a highly effective outpatient treatment for opioid addiction, yet few physicians offer it. Researchers in Washington State examine barriers to prescribing buprenorphine among physicians who have been trained in its use, and they find that a lack of mental health and psychosocial support, time constraints, and a lack of specialty, institutional and partner support were commonly cited barriers. Of the 78 physicians interviewed, only 22 (28 percent) reported prescribing buprenorphine, though almost all reported positive attitudes toward the treatment. (Source: Health News from Medical News Today)
Barriers to primary care physicians prescribing of buprenorphine for opioid addiction
Buprenorphine-naloxone is a highly effective outpatient treatment for opioid addiction, yet few physicians offer it. Researchers in Washington State examine barriers to prescribing buprenorphine among physicians who have been trained in its use, and they find that a lack of mental health and psychosocial support, time constraints, and a lack of specialty, institutional and partner support were commonly cited barriers. Of the 78 physicians interviewed, only 22 (28 percent) reported prescribing buprenorphine, though almost all reported positive attitudes toward the treatment. (Source: Health News from Medical News Today)
Abuse and diversion of buprenorphine sublingual tablets and film
Abstract: Buprenorphine abuse is common worldwide. Rates of abuse and diversion of three sublingual buprenorphine formulations (single ingredient tablets; naloxone combination tablets and film) were compared. Data were obtained from the Researched Abuse, Diversion, and Addiction-Related Surveillance (RADARS®) System Poison Center, Drug Diversion, Opioid Treatment (OTP), Survey of Key Informants’ Patients (SKIP), and College Survey Programs through December 2012. To control for drug availability, event ratios (rates) were calculated quarterly, based on the number of patients filling prescriptions for each formulation (“unique recipients of a dispensed drug,” URDD) and averaged and compared using negative binomial regression. Abuse rates in the OTP, SKIP, and College Survey Programs wer…
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Letter to the Editor
I was very encouraged by the stark reality so clearly delineated by Ms. Coggins (Letter to the Editor, January 2014) concerning the inability of nurse practitioners (NPs) to prescribe the drugs (Suboxone and Zubsolv) now available for opioid dependence. There is an epidemic of opioid deaths, particularly within the New York City area. My particular county of Richmond has the highest rate of opioid deaths. Different legislative laws now require checking a Web site to determine which patient may be seeking additional narcotic medication or doctor shopping. New York has taken firm steps to deal with the high death and addiction rate. (Source: The Journal for Nurse Practitioners)