Category Archives: Methadone Information Feed

Several RSS feeds about methadone treatment and methadone information

The Impact of Prior Authorization on Buprenorphine Dose, Relapse Rates, and Cost for Massachusetts Medicaid Beneficiaries with Opioid Dependence

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ConclusionPrior authorization policies strategically targeted by dose level appear to successfully reduce use of higher than recommended buprenorphine doses. Savings from these policies are modest and may be accompanied by brief increases in relapse rates. Lower doses may decrease diversion of buprenorphine. (Source: Health Services Research)

Detoxification treatments for opiate dependent adolescents.

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CONCLUSIONS: It is difficult to draw conclusions on the basis of two trials with few participants. Furthermore, the two studies included did not consider the efficacy of methadone that is still the most frequent drug utilised for the treatment of opioid withdrawal. One possible reason for the lack of evidence could be the difficulty in conducting trials with young people due to practical and ethical reasons.
PMID: 24777492 [PubMed – as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)

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Detoxification treatments for opiate dependent adolescents.

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CONCLUSIONS: It is difficult to draw conclusions on the basis of two trials with few participants. Furthermore, the two studies included did not consider the efficacy of methadone that is still the most frequent drug utilised for the treatment of opioid withdrawal. One possible reason for the lack of evidence could be the difficulty in conducting trials with young people due to practical and ethical reasons.
PMID: 24777492 [PubMed – as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)

Behavioural treatment combined with buprenorphine does not reduce opioid use compared with buprenorphine alone

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Question Question: In the treatment of opioid dependence, does the addition of behavioural treatment to buprenorphine reduce opioid use compared with buprenorphine alone? Patients: In total, 202 people meeting Diagnostic and Statistical Manual of Mental Disorders, 4th edition, Text Revised (DSM-IV-TR) criteria for opioid dependence. Participants had to have good general medical and psychiatric health, no sensitivity to buprenorphine or naloxone, and no dependence on alcohol, benzodiazepines or any other drug. Setting: Outpatient clinical research centre in Los Angeles, California, USA. Intervention: In total, 16 weeks of buprenorphine with medical management plus either cognitive behavioural therapy (CBT, n=53), contingency management (CM, n=49), both CBT and CM (CBT+CM, n=49) or no b…

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Behavioural treatment combined with buprenorphine does not reduce opioid use compared with buprenorphine alone

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Question Question: In the treatment of opioid dependence, does the addition of behavioural treatment to buprenorphine reduce opioid use compared with buprenorphine alone? Patients: In total, 202 people meeting Diagnostic and Statistical Manual of Mental Disorders, 4th edition, Text Revised (DSM-IV-TR) criteria for opioid dependence. Participants had to have good general medical and psychiatric health, no sensitivity to buprenorphine or naloxone, and no dependence on alcohol, benzodiazepines or any other drug. Setting: Outpatient clinical research centre in Los Angeles, California, USA. Intervention: In total, 16 weeks of buprenorphine with medical management plus either cognitive behavioural therapy (CBT, n=53), contingency management (CM, n=49), both CBT and CM (CBT+CM, n=49) or no b…

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