Aims: The favorable clinical characteristics and improved treatment outcomes for prescription opioid dependent (POD) patients, and modest severity of withdrawal symptoms with buprenorphine/naloxone (bup/nx), have led physicians to offer detoxification with bup/nx for POD patients. We sought to determine whether bup/nx stabilization followed by detoxification (DTX) or maintenance (MTN) leads to greater reduction in illicit opioid use and treatment completion among POD patients treated in primary care. (Source: Drug and Alcohol Dependence)

Aims: The buprenorphine/naloxone (Bup/Nal)combination for the treatment of opioid dependence is available in two forms – sublingual film and tablet. Recent studies demonstrated that treatment with film leads to improved treatment retention and lower healthcare costs. In March 2013 generic tablets appeared on the market. A budget impact model was built to compare health care expenditures based on current market shares of Bup/Nal film and generic Bup/Nal tablet. (Source: Drug and Alcohol Dependence)

Aims: To assess whether response to Cognitive Behavioral Therapy (CBT) differed between primarily prescription opioid users (POU) and primarily heroin users (HU) receiving primary care buprenorphine/naloxone (BUP) treatment with physician management (PM). (Source: Drug and Alcohol Dependence)

This study extends the comparison of diversion and abuse rates between buprenorphine sublingual formulations. (Source: Drug and Alcohol Dependence)

Aims: The favorable clinical characteristics and improved treatment outcomes for prescription opioid dependent (POD) patients, and modest severity of withdrawal symptoms with buprenorphine/naloxone (bup/nx), have led physicians to offer detoxification with bup/nx for POD patients. We sought to determine whether bup/nx stabilization followed by detoxification (DTX) or maintenance (MTN) leads to greater reduction in illicit opioid use and treatment completion among POD patients treated in primary care. (Source: Drug and Alcohol Dependence)

Aims: The buprenorphine/naloxone (Bup/Nal)combination for the treatment of opioid dependence is available in two forms – sublingual film and tablet. Recent studies demonstrated that treatment with film leads to improved treatment retention and lower healthcare costs. In March 2013 generic tablets appeared on the market. A budget impact model was built to compare health care expenditures based on current market shares of Bup/Nal film and generic Bup/Nal tablet. (Source: Drug and Alcohol Dependence)

Aims: To assess whether response to Cognitive Behavioral Therapy (CBT) differed between primarily prescription opioid users (POU) and primarily heroin users (HU) receiving primary care buprenorphine/naloxone (BUP) treatment with physician management (PM). (Source: Drug and Alcohol Dependence)

Aims: The approval of extended release injectable naltrexone suspension (XR-NTX) has introduced a new option for treating opioid addiction, but the absence of physiological opioid dependence is a necessary and challenging first step for starting therapy. Outpatient detoxification gives poor results and inpatient detoxification is either unavailable or too brief for the physiological effects of opioids to resolve. We summarize findings from an open label study that tested whether the transition from opioid addiction to XR-NTX can be safely and effectively performed in an office-based setting using very low dose oral naltrexone and buprenorphine/naloxone (NTX/BUP). (Source: Drug and Alcohol Dependence)

Aims: The approval of extended release injectable naltrexone suspension (XR-NTX) has introduced a new option for treating opioid addiction, but the absence of physiological opioid dependence is a necessary and challenging first step for starting therapy. Outpatient detoxification gives poor results and inpatient detoxification is either unavailable or too brief for the physiological effects of opioids to resolve. We summarize findings from an open label study that tested whether the transition from opioid addiction to XR-NTX can be safely and effectively performed in an office-based setting using very low dose oral naltrexone and buprenorphine/naloxone (NTX/BUP). (Source: Drug and Alcohol Dependence)

Aims: The purpose of this study was to evaluate the demographic, infectious disease status and clinical severity of dependence among heroin users compared to non-prescribed opioid analgesic users in a group of opioid dependent young adults seeking treatment with buprenorphine/naloxone. (Source: Drug and Alcohol Dependence)