Authors: Wallace M
PMID: 21853690 [PubMed – in process] (Source: Australian Nursing Journal)
Monthly Archives: June 2011
Transfer from high dose methadone to buprenorphine/naloxone.
Authors: Wallace M
PMID: 21853690 [PubMed – in process] (Source: Australian Nursing Journal)
Transfer from high dose methadone to buprenorphine/naloxone.
Authors: Wallace M
PMID: 21853690 [PubMed – in process] (Source: Australian Nursing Journal)
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HOT TOPICS In Buprenorphine Treatment
The American Psychiatric Association is offering a new webinar as part of the CSAT-Funded Physicians’ Clinical Support System-Buprenorphine (PCSS-B).
This webinar on Tuesday, July 12, 2011 will be presented by Dr. David Fiellin and Dr. Jeannette Tetrault of the Yale University School of Medicine.
This presentation will cover common medical co-morbidities seen in patients receiving buprenorphine in the office-based setting.
Click here for more information.
Register at https://www2.gotomeeting.com/register/183155506
Differential Pharmacological Actions of Methadone and Buprenorphine in Human Embryonic Kidney 293 Cells Coexpressing Human μ-Opioid and Opioid Receptor-Like 1 Receptors.
In this study, we compared their effects on adenylate cyclase (AC) activity in human embryonic kidney (HEK) 293 cells stably overexpressing human μ-opioid receptor (MOR) and nociceptin/opioid receptor-like 1 receptor (ORL1) simultaneously. After acute exposure, methadone inhibited AC activity; however, buprenorphine induced compromised AC inhibition. When naloxone was introduced after 30 min incubation with methadone, the AC activity was enhanced. This was not observed in the case of buprenorphine. Enhancement of the AC activity was more significant when the incubation lasted for 4 h, and prolonged exposure to buprenorphine elevated the AC activity as well. The removal of methadone and buprenorphine by washing also obtained similar AC superactivation as that revealed by naloxone challen…
Differential Pharmacological Actions of Methadone and Buprenorphine in Human Embryonic Kidney 293 Cells Coexpressing Human μ-Opioid and Opioid Receptor-Like 1 Receptors.
In this study, we compared their effects on adenylate cyclase (AC) activity in human embryonic kidney (HEK) 293 cells stably overexpressing human μ-opioid receptor (MOR) and nociceptin/opioid receptor-like 1 receptor (ORL1) simultaneously. After acute exposure, methadone inhibited AC activity; however, buprenorphine induced compromised AC inhibition. When naloxone was introduced after 30 min incubation with methadone, the AC activity was enhanced. This was not observed in the case of buprenorphine. Enhancement of the AC activity was more significant when the incubation lasted for 4 h, and prolonged exposure to buprenorphine elevated the AC activity as well. The removal of methadone and buprenorphine by washing also obtained similar AC superactivation as that revealed by naloxone challen…
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Differential Pharmacological Actions of Methadone and Buprenorphine in Human Embryonic Kidney 293 Cells Coexpressing Human μ-Opioid and Opioid Receptor-Like 1 Receptors.
In this study, we compared their effects on adenylate cyclase (AC) activity in human embryonic kidney (HEK) 293 cells stably overexpressing human μ-opioid receptor (MOR) and nociceptin/opioid receptor-like 1 receptor (ORL1) simultaneously. After acute exposure, methadone inhibited AC activity; however, buprenorphine induced compromised AC inhibition. When naloxone was introduced after 30 min incubation with methadone, the AC activity was enhanced. This was not observed in the case of buprenorphine. Enhancement of the AC activity was more significant when the incubation lasted for 4 h, and prolonged exposure to buprenorphine elevated the AC activity as well. The removal of methadone and buprenorphine by washing also obtained similar AC superactivation as that revealed by naloxone challen…
Table of Contents
AbstractNAATP: Goodbye to Last Year, Hello to Health Reform, New CEOTASC Stays Focused on Reform Despite Illinois Budget ChallengesChildhood ADHD Found to Predict SUDs 10 Years LaterFDA Says Okay to Give Vivitrol or Suboxone Without CounselingCalifornia Set to Eliminate ADP; Counties Would Administer FundsBriefly NotedResourcesComing up (Source: Alcoholism and Drug Abuse Weekly)
Table of Contents
AbstractNAATP: Goodbye to Last Year, Hello to Health Reform, New CEOTASC Stays Focused on Reform Despite Illinois Budget ChallengesChildhood ADHD Found to Predict SUDs 10 Years LaterFDA Says Okay to Give Vivitrol or Suboxone Without CounselingCalifornia Set to Eliminate ADP; Counties Would Administer FundsBriefly NotedResourcesComing up (Source: Alcoholism and Drug Abuse Weekly)
Table of Contents
AbstractNAATP: Goodbye to Last Year, Hello to Health Reform, New CEOTASC Stays Focused on Reform Despite Illinois Budget ChallengesChildhood ADHD Found to Predict SUDs 10 Years LaterFDA Says Okay to Give Vivitrol or Suboxone Without CounselingCalifornia Set to Eliminate ADP; Counties Would Administer FundsBriefly NotedResourcesComing up (Source: Alcoholism and Drug Abuse Weekly)