Aims: Prescription opioid (PO) dependence frequently co-occurs with chronic pain. Prior studies did not find poorer buprenorphine-naloxone (BUP-NLX) outcomes in chronic pain patients, but more dynamic indicators of chronic pain may impact treatment. We hypothesized that greater pain volatility would predict opioid use during BUP-NLX taper in adults with PO dependence and chronic pain. (Source: Drug and Alcohol Dependence)