Buprenorphine: Less Is More

Author: Breezy_Ann

Posted: Sun Oct 02, 2011 11:41 pm

Ok, this my last post because this going no where. You did not prove me wrong. We were talking about doses above and below 4mg. 4mg is a ceiling level at which the receptors are saturated. Once again you yourself said so and that doses below cause more of an euphoric feeling, your words not mine. You assumed we were talking about the ceiling at which a person gets no more benefit from sub, why I do not know because that has nothing to do with our discussion. We were simply using the same word for two different ceiling properties the med has.

I read thru everyone of your sources and not one says a patient on maintenence for addiction would do better at a lower dose. You mainly posted about a study using bup on non opiate tolerant people for depression. We are not taking it for depression, we are taking it for addiction. In one of your links it even says people who taper and feel fine at .05-1mg and can feel fine are no more addicted than a non opiate tolerant person and are merely using it for depression. Your clinks also say that Bupe is only a powerful agonist at low doses because when it reaches the "ceiling" I was talking about it does not continue to get stronger like full agonists, therefore Bupe does not raise your tolerance above that level unlike full agonists that will increase tolerance. They even have a graph that is exactly the same as Dr. J’s.

So I saw nothing in any of the links you posted that remotely suggests what you are saying is true. Infact I found the opposite, everything on the NAABT link you posted follows exactly what I was saying and what Dr. Junig says. Did you watch the links I posted. I assure you that you will not find a Dr, more educated on bup than Dr. Junig.

Like I said I am done with this thread because it is like walking in a circle, I wish you the best on you low dose and hope that one day you will see that what people need out of sub is as individual as anythin else about us.