Author: TwinCitiesHardcore

Posted: Thu Feb 28, 2013 4:00 pm

There is no linear equation between buprenorphine and full agonists such as the Oxycodone you referenced. Sure, 1mg buprenorphine may be roughly equivalent to 20mg Oxycodone, 2mg buprenorphine may be equivalent to 40mg oxycodone and 4mg buprenorphine may be equivalent to 60mg Oxycodone. But that’s where the opioid effects of buprenorphine begin to diminish. Buprenorphine is a PARTIAL-agonist with a ceiling effect on opioid effects whereas oxycodone, methadone, heroin, morphine, fentanyl are all agonists with no ceiling effect on opioid effect; so though 4mg of buprenorphine is roughly equivalent to 60mg oxycodone, 6mg of buprenorphine is also equivalent to 60mg, 16mg buprenorphine is also equivalent to 60mg Oxycodone and 32mg buprenorphine is equivalent to 60mg oxycodone. Once the cieling of buprenorphine’s effect is reached, there is no going above it!

T