Using scopolamine to treat withdrawal?

Author: slipper

Posted: Tue Jan 24, 2012 8:49 pm

tearj3rker wrote:
Firstly I should say that I’m no medical professional. I’m just an opioid dependent guy who reads a lot. It’s not smart to experiment with this use until more research is done.

Tonight I stumbled on some info about Scopolamine while reading about diving. Scopolamine is the drug used in travel sickness pills, and naturally occurs in the Datura flower and a few other naughty garden plants teenagers like to eat.

I’ll stop typing and just paste the interesting bits.

Quote:
Clinical study of scopolamine detoxification for the treatment of heroin addicts

Yang G, Xu K, Luo Q.

OBJECTIVE:
To evaluate the efficacy of treatment of heroin addicts (n = 100) by scopolamine detoxification (10 days program).

METHODS:
Methadone detoxification (10 days program) group (n = 50) and clonidine treated group (n = 50) served as controls.

RESULTS:

The scores of abstinence syndrome in scopolamine detoxification group were lower that those in clonidine treated group in the first three days of protocol, but this difference disappeared in the late stage of treatment. While scopolamine detoxification was effective as methadone detoxification in the control of abstinence syndrome during the first five days of treatment but the difference in the scores of abstinence syndrome between scopolamine and methadone group was observed during the late five days of protocol. The side-effects produced by scopolamine in general were dry mouth, somnolence, tachycardia, blurred vision and so on, which relieved gradually or disappeared with decreasing of its doses.

CONCLUSION:

Scopolamine does not result in potential dependence and has definite curative effect in the treatment of heroin addiction.

Quote:
Addiction

Scopolamine has been used in the past to treat addiction to drugs such as heroin and cocaine. The patient was given frequent doses of scopolamine until they were delirious. This treatment was maintained for 2 to 3 days after which they were treated with pilocarpine. After recovering from this they were said to have lost the acute craving to the drug to which they were addicted.[7]

Currently, scopolamine is being investigated for its possible usefulness alone or in conjunction with other drugs in treating nicotine addiction.[citation needed] The mechanism by which it mitigates withdrawal symptoms is different from that of clonidine meaning that the two drugs can be used together without duplicating or canceling out the effects of each other.

I went a bit further, and found there’s been studies into scopolamine and the use of travel sickness patches for depression with promising results, so for those like me who are dual diagnosed it may be worth watching this space.

But, like with Suboxone, there’s no such thing as a free ride. Looks like Scopolamine has its own withdrawal process that sounds a bit nasty, if it’s taken 3+ days.

[b]Tear,

I am really afraid of scopolamine. WE used to give it in surgery to help dry up the mouth and prevent laringiospasm.

When I had my first child I was in a little small town hospital and basically had him cold turkey. They gave me a shot of demerol with scopolamine and I had acute effects from the scope. I felt like I was dying, my heart was beating in my throat, my vision was blurred an I had acute tachycardia. It absolutely ruined the nice effect the demerol would have had.
I will never take that drug again..it really scared me….but that is just my experence. If it can help others, then I all for that. It is just not for me.

Slipper[/b]