Author: tearj3rker

Posted: Fri Jul 06, 2012 2:48 am

Another thing about all this stuff is that it’s not an exact science in that there’s variability from person to person. Things like race, general rate of metabolism, body type, sex etc all play a role, as well as plain old genetic variations. In medication like buprenorphine which is broken down by more than one enzyme, it may be that some people use CYP2D6 more to break it down and CYP3A4 less. I always found SSRI’s sped up my metabolism of Sub a LOT … while many people don’t have this effect.

ie I also used speed while on heroin quite a bit and I didn’t have that problem. In fact, there were times I used speed to kick heroin, because the stimulant effect of the speed seemed to push me through my withdrawal.

Stimulant drugs though can speed up metabolism of everything.