Author: koval115
Posted: Mon Jan 23, 2012 1:04 pm
The Captain wrote: |
(since i’m new, it won’t let me link bc of spammers, but just google "suboxone alcoholic solutions" or I’ll detail the method myself here and edit this when it will let me link)
Have you guys seen this? Its about making an alcoholic solution of buprenorphine and having a higher bioavailability and making solutions for titrating your dose to sub mg levels. Some studies say that the BA for an alcoholic solution is close to 70% higher than tablets alone. Bioavailability 40-50% (sublingual, from ethanolic solution) 35-40% (sublingual, high-dose tablet) ~50% (transdermal) ~50-60% (intranasal) The bioavailability from sublingual pills is very low, usually like 30-35%. The sublingual films is a little higher. But I can say for sure this method works…imagine getting 2x or more use from your suboxone! This uses ABSOLUTELY MINUSCULE amounts of ethanolic solutions (high-proof rum or vodka). Please don’t confuse this with combining suboxone with alcohol in any way. We are talking some .25ML which is a few drops, not actually drinking alcohol. It’s a well known fact in medicine that alcoholic (specifically ethanol) solutions increases the permeability of the mucous membrane under the tongue. In the 1st link and throughout the thread there are detailed methods of doing this both with the film and pills. And whats more, you can make a larger solution for tapering to sub mg doses. This makes titrating you dose easy, and with the increased bioavailability you can make your suboxone last way longer. It’s also beneficial bc if you use alcohol in a solution for long term use it won’t degrade or become infected with bacteria. One month of Rx suboxone film (for me 60) can last me like nearly a year and half using this method. I’m down to less than 1mg/day. Please guys, if you’d like to know more, check out the link at the top, or just ask! It really works! And good luck to all folks tapering. It can be done. I’ve been using opiates for over a decade and had a tolerance that only 100mg of methadone could touch…and now I’m skipping days and down to a tiny tiny dose. There is hope |
this is the way u can make transdermal paths works faster. just put piece of path into vodka for night, in the moarning just shake it, take out rest of path, spill mixture on cottonwool and put under ur tongue for 20-25 minutes. if u want to know more about transdermal paths write pm:)