Author: news_poster
Posted: Tue Feb 28, 2012 3:00 am
Conclusions: Methadone inhibited the CYP2D6�mediated metabolism of tramadol to M1. Hence, as the degree of opioid analgesia is largely dependent on M1 formation, methadone maintenance patients may not receive adequate analgesia from oral tramadol.© 2012 The Authors. British Journal of Clinical Pharmacology © 2012 The British Pharmacological Society (Source: British Journal of Clinical Pharmacology)
Source: MedWorm Query: Buprenorphine
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