Buprenorphine and Naloxone Compared With Methadone Treatment in Pregnancy.

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CONCLUSION:: In a cohort of pregnant patients treated with either methadone or buprenorphine and naloxone in pregnancy, newborns exposed to maternal buprenorphine and naloxone had less frequent neonatal abstinence syndrome. Additionally, neonates exposed to buprenorphine and naloxone had shorter overall hospitalization lengths. LEVEL OF EVIDENCE:: II.
PMID: 25569005 [PubMed – as supplied by publisher] (Source: Obstetrics and Gynecology)