Total Joint Arthroplasty in Patients Taking Methadone or Suboxone Preoperatively for Prior Heroin Addiction: A Prospective Matched Cohort Study

Preoperative narcotic use has been associated with poor outcomes following total joint arthroplasty (TJA). The purpose of this study is to compare clinical outcomes of patients undergoing elective TJA while concurrently being treated with methadone or buprenorphine/naloxone for prior heroin addiction to a matched control group. (Source: The Journal of Arthroplasty)

Overdose Reversal Drug Now Available To Every U.S. High School Free Of Charge

Any high school in the U.S. that wants to carry an emergency opioid overdose reversal kit will now be able to get one free of charge, thanks to a new initiative announced Monday by the Clinton Foundation and the drug’s manufacturer. Adapt Pharma, manufacturers of a nasal-spray form of naloxone, also known as Narcan, has partnered with the Clinton Health Matters Initiative to further expand access to the life-saving drug, the two groups said at the final day of the Clinton Health Matters Initiative Activation Summit. Naloxone is nonaddictive, nontoxic and easy to administer, especially through nasal application. It reverses the effects of an opioid overdose by essentially blocking the opioid receptors that heroin and many prescription painkillers target. The U.S. Food and Drug Administ…

Overdose Reversal Drug Now Available To Every U.S. High School Free Of Charge

Any high school in the U.S. that wants to carry an emergency opioid overdose reversal kit will now be able to get one free of charge, thanks to a new initiative announced Monday by the Clinton Foundation and the drug’s manufacturer. Adapt Pharma, manufacturers of a nasal-spray form of naloxone, also known as Narcan, has partnered with the Clinton Health Matters Initiative to further expand access to the life-saving drug, the two groups said at the final day of the Clinton Health Matters Initiative Activation Summit. Naloxone is nonaddictive, nontoxic and easy to administer, especially through nasal application. It reverses the effects of an opioid overdose by essentially blocking the opioid receptors that heroin and many prescription painkillers target. The U.S. Food and Drug Administ…

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Akorn Launches Buprenorphine/Naloxone Sublingual Tablets and Tobramycin Injection

LAKE FOREST, Ill., Jan. 19, 2016 — (Healthcare Sales & Marketing Network) — Akorn, Inc. (AKRX), a leading specialty generic pharmaceutical company, today announced that it has launched Buprenorphine and Naloxone Sublingual Tablets CIII in 2mg/0.5mg and 8… Biopharmaceuticals, Generics, Product LaunchAkorn, Buprenorphine, Naloxone, Tobramycin (Source: HSMN NewsFeed)

Akorn Launches Buprenorphine/Naloxone Sublingual Tablets and Tobramycin Injection

LAKE FOREST, Ill., Jan. 19, 2016 — (Healthcare Sales & Marketing Network) — Akorn, Inc. (AKRX), a leading specialty generic pharmaceutical company, today announced that it has launched Buprenorphine and Naloxone Sublingual Tablets CIII in 2mg/0.5mg and 8… Biopharmaceuticals, Generics, Product LaunchAkorn, Buprenorphine, Naloxone, Tobramycin (Source: HSMN NewsFeed)

Malmö Treatment Referral and Intervention Study (MATRIS)—effective referral from syringe exchange to treatment for heroin dependence: a pilot randomized controlled trial

ConclusionsA randomized controlled trial in a syringe exchange programme showed no evidence that a strength‐based case management intervention improved attendance for treatment over referral alone. Attendance rates were high in both groups. (Source: Addiction)

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Malmö Treatment Referral and Intervention Study (MATRIS)—effective referral from syringe exchange to treatment for heroin dependence: a pilot randomized controlled trial

ConclusionsA randomized controlled trial in a syringe exchange programme showed no evidence that a strength‐based case management intervention improved attendance for treatment over referral alone. Attendance rates were high in both groups. (Source: Addiction)

Sustained-Release Buprenorphine (RBP-6000) Blocks the Effects of Opioid Challenge With Hydromorphone in Subjects With Opioid Use Disorder

This study demonstrated that RBP-6000 at a 300 mg dose provides durable and potent blockade of the subjective effects and reinforcing efficacy of hydromorphone in subjects with moderate or severe opioid use disorder. (Source: Journal of Clinical Psychopharmacology)

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Sustained-Release Buprenorphine (RBP-6000) Blocks the Effects of Opioid Challenge With Hydromorphone in Subjects With Opioid Use Disorder

This study demonstrated that RBP-6000 at a 300 mg dose provides durable and potent blockade of the subjective effects and reinforcing efficacy of hydromorphone in subjects with moderate or severe opioid use disorder. (Source: Journal of Clinical Psychopharmacology)

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Factors associated with non-adherence to Buprenorphine-naloxone among opioid dependent African-Americans: A retrospective chart review.

CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Our results indicate that alcohol and illicit substance use is associated with non-adherence to BUP-naloxone treatment, and suggests that CBT and efforts to promote abstinence from non-opioid substance use may improve adherence among African-Americans. These findings contribute to growing literature on understanding adherence to BUP-naloxone, which is critical to reduce morbidity and mortality. (Am J Addict 2016;XX:1-8).
PMID: 26749158 [PubMed – as supplied by publisher] (Source: American Journal on Addictions)